Sunvozertinib
| CAS No. | 2370013-12-8 | Cat. No. | BCP46584 |
| Name | Sunvozertinib | ||
| Synonyms | DZD 9008; (DZD-9008; DZD9008; | ||
| Formula | C29H35ClFN7O3 | M. Wt | 584.08 |
| Description | Sunvozertinib (DZD9008) is an effective inhibitor of ErbBs (EGFR, Her2, especially mutants) and BTK. Sunvozertinib showed EGFR exon 20 NPH insertion, EGFR exon 20 ASV insertion, EGFR L858R and T790M mutations, and IC50 of Her2 exon 20 YVMA and EGFR WT A431 They are 20.4, 20.4, 1.1, 7.5 and 80.4 nM respectively. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR BTK | ||
Structure
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