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Sunvozertinib Chemical Structure

Sunvozertinib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP46584CAS No. :2370013-12-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2370013-12-8 Cat. No. BCP46584
Name Sunvozertinib
Synonyms DZD 9008; (DZD-9008; DZD9008;
SMILES CC(C)(C1=CC(=C(C=C1NC2=NC(=NC=C2)NC3=C(C=C(C(=C3)NC(=O)C=C)N4CCC(C4)N(C)C)OC)Cl)F)O
Chemical Name
Formula C29H35ClFN7O3 M. Wt 584.08
Purity 98% Storage Store at 4-8°C
Description Sunvozertinib (DZD9008) is an effective inhibitor of ErbBs (EGFR, Her2, especially mutants) and BTK. Sunvozertinib showed EGFR exon 20 NPH insertion, EGFR exon 20 ASV insertion, EGFR L858R and T790M mutations, and IC50 of Her2 exon 20 YVMA and EGFR WT A431 They are 20.4, 20.4, 1.1, 7.5 and 80.4 nM respectively.
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