SN-38-D3
| CAS No. | 718612-49-8 | Cat. No. | BCP49629 |
| Name | SN-38-D3 | ||
| Synonyms | NK012-D3;[2H3]-SN-38; | ||
| Formula | C22H20N2O5 | M. Wt | 392.4 |
| Description | SN-38-D3 is the deuterium labeled SN-38. SN-38 (NK012) is an active metabolite of the Topoisomerase I inhibitor Irinotecan. SN-38 (NK012) inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. | ||
| Pathways | Cell Cycle/DNA Damage Others Pathway | ||
| Targets | Topoisomerase ADC Related Autophagy | ||
Structure
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