Y-27632 Dihydrochloride Hydrate
| CAS No. | 331752-47-7 | Cat. No. | BCP26044 |
| Name | Y-27632 Dihydrochloride Hydrate | ||
| Synonyms | Y-27632 monohydrate dihydrochloride；Y27632 Dihydrochloride Hydrate; Y 27632 Dihydrochloride Hydrate; | ||
| Formula | C14H25Cl2N3O2 | M. Wt | 338.3 |
| Description | Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriuretic peptide production, cell size, protein synthesis, and myofibrillar organization. Y27632 prevents dimethylnitrosamine-induced hepatic fibrosis in rats, increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium, affects initial heart myofibrillogenesis in cultured chick blastoderm, promotes the proliferation and cell cycle progression of cultured astrocyte from spinal cord. | ||
| Related Products | 146986-50-7（Y27632） 129830-38-2（Y-27632 dihydrochloride） | ||
| Pathways | Cell Cycle/DNA Damage TGF beta/Smad Wnt/Stem Cell | ||
| Targets | ROCK | ||
Structure
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