CHIR-99021 trihydrochloride
| CAS No. | 1782235-14-6 | Cat. No. | BCP26069 |
| Name | CHIR-99021 trihydrochloride | ||
| Synonyms | CT99021 trihydrochloride;CHIR-99021 3HCl; GSK 3 inhibitor XVI; GSK 3IXV; | ||
| Formula | M. Wt | 574.72 | |
| Description | CHIR-99021 trihydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. CHIR-99021 trihydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. CHIR-99021 trihydrochloride is also a potent Wnt/β-catenin signaling pathway activator. CHIR-99021 trihydrochloride enhances mouse and human embryonic stem cells self-renewal. CHIR-99021 trihydrochloride induces autophagy. | ||
| Pathways | Wnt/Stem Cell PI3K/Akt/mTOR | ||
| Targets | GSK3 Wnt | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.