WHI-P 97
| CAS No. | 211555-05-4 | Cat. No. | BCP29062 |
| Name | WHI-P 97 | ||
| Synonyms | WHI-P97; WHIP 97; WHIP97; WHIP-97; | ||
| Formula | C16H13Br2N3O3 | M. Wt | 455.11 |
| Description | WHI-P97 is a JAK3 inhibitor. WHI-P97 had an estimated Ki value of 0.09 microM from modeling studies and a measured IC50 value of 2.5 microM in EGFR kinase inhibition assays. WHI-P97 effectively inhibited the in vitro invasiveness of EGFR-positive human cancer cells in a concentration-dependent manner. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
| Targets | JAK | ||
Structure
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