LUT-014
| CAS No. | 2274819-46-2 | Cat. No. | BCP30636 |
| Name | LUT-014 | ||
| Synonyms | LUT 014;LUT014; | ||
| Formula | C27H19F3N8O | M. Wt | 528.50 |
| Description | LUT014 is a topical B-Raf Inhibitor, a proprietary, first-in-class, small molecule allowing administration of EGFR (Epidermal Growth Factor Receptor) Inhibitors to patients without interruptions caused by typical cutaneous side effects.Leveraging the paradoxical effect of B-Raf Inhibitors, LUT014 decreases dermal toxicities associated with EGFR Inhibitors, thus reducing acneiform lesions associated with such therapy. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway MAPK Pathway | ||
| Targets | EGFR Raf | ||
Structure
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