ZD-4190
| CAS No. | 413599-62-9 | Cat. No. | BCP30854 |
| Name | ZD-4190 | ||
| Synonyms | ZD 4190;ZD4190; | ||
| Formula | C19H16BrFN6O2 | M. Wt | 459.28 |
| Description | ZD-4190, a substituted 4-anilinoquinazoline, is a potent, orally available inhibitor of the vascular endothelial cell growth factor receptor 2 (VEGFR2) and of epidermal growth factor receptor (EGFR) signalling, with broad-spectrum antitumor efficacy. ZD-4190 is one of a series of VEGF RTK inhibitors that may have utility in the treatment of a range of histologically diverse solid tumor types. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | VEGFR EGFR | ||
Structure
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