IC-87114
| CAS No. | 371242-69-2 | Cat. No. | BCP01922 |
| Name | IC-87114 | ||
| Synonyms | IC87114;IC 87114; | ||
| Formula | C22H19N7O | M. Wt | 397.43 |
| Description | IC-87114 is a potent and ATP-competitive PI3K p110δ isoform-selective inhibitor (IC50 = 60 nM). It Inhibits p110α, p110β and p110γ only at much higher concentrations. It does not inhibit other PIK-related kinases such as ATM, ATR, DNA-PK, and mTOR even at concentrations up to 100 µM. | ||
| Pathways | Cell Cycle/DNA Damage PI3K/Akt/mTOR | ||
| Targets | ATM/ATR DNA PK PI3K | ||
Structure
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