TAK-779
| CAS No. | 229005-80-5 | Cat. No. | BCP28073 |
| Name | TAK-779 | ||
| Synonyms | TAK 779; TAK779;Takeda 779;Takeda-779;Takeda779; | ||
| Formula | C33H39N2O2.Cl | M. Wt | 531.14 |
| Description | TAK-779 is a C-C chemokine receptor type 5 (CCR5) receptor antagonist potentially for the treatment of HIV infection. Treatment with TAK-779 reduced incidence and severity of experimental autoimmune encephalomyelitis. It strongly inhibited migration of CXCR3/CCR5 bearing CD4+, CD8+ and CD11b+ leukocytes to the CNS. TAK-779 did not reduce proliferation of anti-myelin oligodendrocyte glycoprotein T cells, the production of IFN-gamma by T cells or CXCR3 expression on T cells. In addition, TAK-779 did not affect production of IL-12 by antigen-presenting cells, CCR5 induction on T cells and the potential of myelin oligodendrocyte glycoprotein-specific T cells to transfer experimental autoimmune encephalomyelitis. | ||
| Pathways | Microbiology/Virology GPCR/G Protein | ||
| Targets | HIV CCR | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.