NVP-BSK805 2HCl
CAS No. | 1942919-79-0 | Cat. No. | BCP23423 |
Name | NVP-BSK805 2HCl | ||
Synonyms | NVP-BSK805 dihydrochloride;BSK805 dihydrochloride;NVPBSK805;NVP BSK805;NVP-BSK805; | ||
Formula | C27H28F2N6O.2HCl | M. Wt | 563.47 |
Description | NVP-BSK805 dihydrochloride is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics | ||
Targets | JAK |
Structure

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