NVP-BSK805 2HCl

  • Chemical Properties
CAS No. 1942919-79-0 Cat. No. BCP23423
Name NVP-BSK805 2HCl
Synonyms NVP-BSK805 dihydrochloride;BSK805 dihydrochloride;NVPBSK805;NVP BSK805;NVP-BSK805;
Formula C27H28F2N6O.2HCl M. Wt 563.47
  • Biological Activity
Description NVP-BSK805 dihydrochloride is an ATP-competitive JAK2 inhibitor, with IC50s of 0.48 nM, 31.63 nM, 18.68 nM, and 10.76 nM for JAK2 JH1 (JAK homology 1), JAK1 JH1, JAK3 JH1, and TYK2 JH1, respectively.
Pathways Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics 
Targets JAK 

Structure

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