Chebulinic acid
| CAS No. | 18942-26-2 | Cat. No. | BCP09990 |
| Name | Chebulinic acid | ||
| Synonyms | NSC69862;NSC-69862;NSC 69862;Eutannin; | ||
| Formula | C41H32O27 | M. Wt | 956.68 |
| Description | Chebulinic Acid is a potent protectant against glutamate-induced neuronal cell death. It has been shown to significantly reduce intracellular reactive oxygen species (ROS) production and Ca2+ influx induced by glutamate, decrease the phosphorylation of mitogen-activated protein kinases (MAPKs), including ERK1/2, JNK, and p38, as well as inhibit pro-apoptotic Bax and increase anti-apoptotic Bcl-2 protein expression. | ||
| Pathways | Ion Channel/Membrane Transporter Cell Cycle/DNA Damage TGF beta/Smad Wnt/Stem Cell | ||
| Targets | DNA/RNA Synthesis TGF β/Smad Proton Pump | ||
Structure
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