2-D08
| CAS No. | 144707-18-6 | Cat. No. | BCP18314 |
| Name | 2-D08 | ||
| Synonyms | 2D08;2 D08; | ||
| Formula | C15H10O5 | M. Wt | 270.24 |
| Description | 2-D08 is a synthetic flavone that inhibits sumoylation. 2-D08 showed anti-aggregatory and neuroprotective effect.It is also inhibits Axl, IRAK4, ROS1, MLK4, GSK3β, RET, KDR and PI3Kα with IC50 values of 0.49, 3.9, 5.3, 9.8, 11, 11, 17 and 35 nM respectively in biochemical assays. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Protease/Metabolic Enzyme PI3K/Akt/mTOR Wnt/Stem Cell | ||
| Targets | E1 E2 E3 Enzyme TAM Receptor VEGFR GSK3 PI3K | ||
Structure
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