Chlorpromazine hydrochloride

  • Chemical Properties
CAS No. 69-09-0 Cat. No. BCP30284
Name Chlorpromazine hydrochloride
Synonyms Chlorpromazine HCl;
Formula C17H19ClN2S.HCl M. Wt 355.32
  • Biological Activity
Description Chlorpromazine Hydrochloride is the hydrochloride salt form of chlorpromazine, a phenothiazine and traditional antipsychotic agent with anti-emetic activity. Chlorpromazine hydrochloride exerts its antipsychotic effect by blocking postsynaptic dopamine receptors in cortical and limbic areas of the brain, thereby preventing the excess of dopamine in the brain. This leads to a reduction in psychotic symptoms, such as hallucinations and delusions. Chlorpromazine hydrochloride appears to exert its anti-emetic activity by blocking the dopamine receptors in the chemical trigger zone (CTZ) in the brain, thereby relieving nausea and vomiting.
Pathways Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein Others Pathway 
Targets 5 HT Receptor/Serotonin Receptor Dopamine Receptor Potassium Channel Sodium Channel Autophagy 

Structure

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