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Adapalene 结构式

阿达帕林

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP02081CAS号 :106685-40-9纯度:98%
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  • 基本信息与产品描述
CAS号 106685-40-9 货号 BCP02081
中文名 阿达帕林
英文名 Adapalene
中文别名
英文别名 CD-271;CD 271;CD271;Differi;
SMILES
化学名称
分子式 C28H28O3 分子量 412.52
纯度 98% 配送 惯例下常温包邮
产品描述 Adapalene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. Adapalene is possibly more effective than tretinoin 0.025% gel in the treatment of acne vulgaris . Thirty-six rats of either sex were divided into six groups (two control groups, and an etodolac, indomethacin, tretinoin and adapalene group) of six animals each. Each group was given different drugs or chemicals. The inhibitory activities of the drugs were determined on carrageenan-induced rat-paw oedema. The inhibition rate (53.48%) in the tretinoin group was found to be higher thanadapalene and controls (P < 0.05). Adapalene was found to have an inhibition rate of 10.28%, and when compared with the other groups, was found to have no statistically significant anti-inflammatory activity .
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