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CAS号 | 110429-45-3 | 货号 | BCP42805 |
中文名 | m-PEG4-bromide | ||
英文名 | m-PEG4-bromide | ||
中文别名 | 三乙二醇2-溴乙基甲醚;甲基-四聚乙二醇-溴代;1-溴-3,6,9,12-四氧杂十三烷; | ||
英文别名 | 13-Bromo-2,5,8,11-tetraoxatridecane;Triethylene Glycol 2-Bromoethyl Methyl Ether; | ||
SMILES | COCCOCCOCCOCCBr | ||
化学名称 | |||
分子式 | C9H19BrO4 | 分子量 | 271.15 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab. m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency. m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. |
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