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CAS号 | 1496510-51-0 | 货号 | BCP30640 |
中文名 | Relacorilant | ||
英文名 | Relacorilant | ||
中文别名 | |||
英文别名 | CORT125134; CORT-125134; CORT 125134; | ||
SMILES | CN1C=C(C=N1)S(=O)(=O)N2CCC3=CC4=C(CC3(C2)C(=O)C5=NC=CC(=C5)C(F)(F)F)C=NN4C6=CC=C(C=C6)F | ||
化学名称 | |||
分子式 | C27H22F4N6O3S | 分子量 | 586.56 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Relacorilant is a potent, selective and orally bioavailable glucocorticoid receptor antagonist, with a Ki of 7.2 nM in HepG2 TAT assay, and also shows Kis of 12, 81.2, 210 nM for rat, human and monkey glucocorticoid receptor in cell-based assay, respectively; Relacorilant has entered phase 2 clinical study in patients with Cushing’s syndrome. |
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