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CAS号 | 1660117-38-3 | 货号 | BCP35872 |
中文名 | BRD4 Inhibitor-10 | ||
英文名 | BRD4 Inhibitor-10 | ||
中文别名 | |||
英文别名 | BI-894999; BI894999; BI 894999; | ||
SMILES | CC1=CC(=NN(C1=O)C)C2=NC3=CN=C(C=C3N2C(C)C4=CC=CC=C4)C5CCOCC5 | ||
化学名称 | |||
分子式 | C25H27N5O2 | 分子量 | 429.52 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | BRD4 Inhibitor-10 is a potent and selective BET inhibitor potentially useful for the Treatment of hematological malignancies by repression of super-enhancer driven oncogenes. BI-894999 is a highly potent drug, particularly in hematological cell lines (n>40) such as MM, AML and lymphoma. BI 894999 treatment leads to G1 arrest and subsequent apoptosis. BI 894999 is found to regulate a very distinct set of genes. As already known. |
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