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CAS号 | 1817626-54-2 | 货号 | BCP18916 |
中文名 | PF-06650833 | ||
英文名 | PF-06650833 | ||
中文别名 | |||
英文别名 | PF 06650833;PF06650833; PF-6650833; PF 6650833; PF6650833; | ||
SMILES | NC(C1=C(OC)C=C2C(C=CN=C2OC[C@@H]3[C@](CC)[C@](F)C(N3)=O)=C1)=O | ||
化学名称 | |||
分子式 | C18H20FN3O4 | 分子量 | 361.37 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | PF-06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4). RAK4 is located proximal to TLR/IL-1 receptors, and in preclinical studies, inhibits downstream signaling from these receptors. The development of novel small molecule inhibitors of this kinase has the potential to lead to new therapeutics to treat diseases such as rheumatoid arthritis, lupus, and lymphomas. |
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