参考资料
在线咨询
购买咨询即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS号 | 1912445-55-6 | 货号 | BCP29496 |
| 中文名 | BMS-986195 | ||
| 英文名 | BMS-986195 | ||
| 中文别名 | |||
| 英文别名 | BMS986195; BMS986195; | ||
| SMILES | FC1=C(N2CCC[C@H](NC(C#CC)=O)C2)C3=C(NC(C)=C3C)C(C(N)=O)=C1 | ||
| 化学名称 | |||
| 分子式 | C20H23FN4O2 | 分子量 | 370.43 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | BMS-986195 is a potent, covalent, irreversible inhibitor of Bruton’s tyrosine kinase (BTK), a member of the Tec family of non-receptor tyrosine kinases essential in antigen-dependent B-cell signaling and function. BMS-986195 is more than 5000-fold selective for BTK over all kinases outside of the Tec family, and selectivity ranges from 9- to 1010-fold within the Tec family. BMS-986195 inactivated BTK in human whole blood with a rapid rate of inactivation (3.5×10-4 nM-1·min-1) and potently inhibited antigen-dependent interleukin-6 production, CD86 expression and proliferation in B cells (IC50 <1 nM) without effect on antigen-independent measures in the same cells. | ||
在购买和使用瀚香生物产品的过程中，您遇到的任何问题，都可以咨询我们的免费热线：400-099-8200，或者和我们的客服 
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。相关产品推荐
查看更多 >
Tags:BMS-986195 供应商,BMS-986195 购买,BMS-986195 生产,BMS-986195 批量,BMS-986195 供应,BMS-986195 订购,BMS-986195 采购