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瀚香生物(Biochempartner)的Orantinib被文献引用
| CAS号 | 252916-29-3 | 货号 | BCP01984 |
| 中文名 | Orantinib | ||
| 英文名 | Orantinib | ||
| 中文别名 | |||
| 英文别名 | TSU68; TSU 68; TSU-68; SU6668; SU 6668; SU-6668; | ||
| SMILES | O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=CC=C3)=O)=C1C | ||
| 化学名称 | |||
| 分子式 | C18H18N2O3 | 分子量 | 310.35 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Orantinib, also known as TSU-68；SU6668, is an orally bioavailable receptor tyrosine kinase inhibitor. Orantinib binds to and inhibits the autophosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR), thereby inhibiting angiogenesis and cell proliferation. Orantinib also inhibits the phosphorylation of the stem cell factor receptor tyrosine kinase c-kit, often expressed in acute myelogenous leukemia cells. Check for active clinical trials or closed clinical trials using this agent. | ||
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