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| CAS号 | 332348-12-6 | 货号 | BCP30221 |
| 中文名 | 阿巴西普 | ||
| 英文名 | Abatacept | ||
| 中文别名 | |||
| 英文别名 | BMS-188667;BMS 188667;BMS188667;RG2077;RG 2077;RG-2077;CTLA4-Ig; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C3498H5458N922O1090S32 | 分子量 | 92300 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Abatacept is a fusion protein composed of the Fc region of the immunoglobulin IgG1 fused to the extracellular domain of CTLA-4. In order for a T cell to be activated and produce an immune response, an antigen presenting cell must present two signals to the T cell. One of those signals is the major histocompatibility complex (MHC), combined with the antigen, and the other signal is the CD80 or CD86 molecule (also known as B7-1 and B7-2). Abatacept binds to the CD80 and CD86 molecule, and prevents the second signal. Without the second signal, the T cell can't be activated. | ||
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