洛批莫德新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP09909CAS号：585543-15-3纯度：98%

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CAS号	585543-15-3	货号	BCP09909
中文名	洛批莫德
英文名	losmapimod
中文别名
英文别名	GW856553; GW-856553; GW 856553;GW856553X;GSK-AHAB;
SMILES	CC1=C(C=C(C=C1F)C(=O)NC2CC2)C3=NC=C(C=C3)C(=O)NCC(C)(C)C
化学名称
分子式	C22H26FN3O2	分子量	383.2
纯度	98%	配送	惯例下常温包邮
产品描述	Losmapimod is an orally bioavailable inhibitor of the alpha and beta isoforms of p38 mitogen-activated protein kinase (MAPK), with potential immunomodulating and anti-inflammatory activities. Upon oral administration, losmapimod inhibits the activity of p38alpha/beta MAPK, thereby preventing p38alpha/beta MAPK-mediated signaling. This may result in the inhibition of the production of proinflammatory cytokines. p38 MAPK, a serine/threonine protein kinase, plays an important role in regulating the transcription and translation of cytokines involved in inflammation including tumor necrosis factor alpha (TNF-alpha) and interleukin (IL)-1, IL-6 and IL-8.

洛批莫德 新