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CAS号 | 857290-04-1 | 货号 | BCP28049 |
中文名 | PF 915275 | ||
英文名 | PF 915275 | ||
中文别名 | |||
英文别名 | PF-915275; PF915275; | ||
SMILES | N#CC1=CC=C(C2=CC=C(S(NC3=NC(N)=CC=C3)(=O)=O)C=C2)C=C1 | ||
化学名称 | |||
分子式 | C18H14N4O2S | 分子量 | 350.39 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | PF-915275 is a potent and selective 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1) inhibitor (Ki = 2.3 nM) PF-915275 inhibits the conversion of prednisone to prednisolone in human hepatocytes in vitro (EC50 = 15 nM) and has antidiabetic activity in vivo. |
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