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FIPI 结构式

FIPI

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货号 :BCP09746CAS号 :939055-18-2纯度:98%
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  • 基本信息与产品描述
CAS号 939055-18-2 货号 BCP09746
中文名 FIPI
英文名 FIPI
中文别名
英文别名 5-Fluoro-2-Indolyl des-Chlorohalopemide;
SMILES
化学名称
分子式 C23H24FN5O2 分子量 421.47
纯度 98% 配送 惯例下常温包邮
产品描述 FIPI is a potent and selective phospholipase D inhibitor. FIPI attenuate mercury-induced lipid signaling leading to protection against cytotoxicity in aortic endothelial cells. FIPI rapidly blocks in vivo PA production with subnanomolar potency. We were surprised to find that several biological processes blocked by 1-butanol are not affected by FIPI, suggesting the need for re-evaluation of proposed FIPI does inhibit PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis, indicating potential utility for it as a therapeutic for autoimmunity and cancer metastasis.
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