Remetinostat 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP30561CAS号：946150-57-8纯度：98%

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CAS号	946150-57-8	货号	BCP30561
中文名	Remetinostat
英文名	Remetinostat
中文别名
英文别名	SHP-141; SHP 141; SHP141; SHAPE;
SMILES	COC(=O)C1=CC=C(C=C1)OC(=O)CCCCCCC(=O)NO
化学名称
分子式	C16H21NO6	分子量	323.34
纯度	98%	配送	惯例下常温包邮
产品描述	Remetinostat is a topical formulation containing the histone deacetylase (HDAC) inhibitor with potential antineoplastic activity. Upon cutaneous administration, SHP-141 selectively binds to and inhibits HDAC, resulting in an accumulation of highly acetylated histones in the skin (dermis and epidermis), the induction of chromatin remodeling, and the selective transcription of tumor suppressor genes. These events may result in the inhibition of tumor cell division and the induction of tumor cell apoptosis. HDACs, upregulated in many tumor cell types, are a family of metalloenzymes responsible for the deacetylation of chromatin histone proteins. Topical administration of SHP-141 allows for high concentrations of this agent locally while minimizing systemic toxicity.