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CAS号 | 959122-11-3 | 货号 | BCP00238 |
中文名 | A 922500 | ||
英文名 | A 922500 | ||
中文别名 | |||
英文别名 | DGAT-1 Inhibitor 4a; A-922500; A922500; | ||
SMILES | |||
化学名称 | |||
分子式 | C26H24N2O4 | 分子量 | 428.48 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Zucker fatty rats and diet-induced dyslipidemic hamsters are dosed orally with A 922500 (0.03, 0.3, and 3 mg/kg) for 14 days. Serum triglycerides ae significantly reduced by the 3 mg/kg dose of A 922500 in both the Zucker fatty rat (39%) and hyperlipidemic hamster (53%). These serum triglyceride changes are accompanied by significant reductions in free fatty acid levels by 32% in the Zucker fatty rat and 55% in the hyperlipidemic hamster. In addition, high-density lipoprotein-cholesterol is sign |
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