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| CAS号 | 1033805-22-9 | 货号 | BCP02293 |
| 中文名 | 特罗司他乙酯 | ||
| 英文名 | Telotristat ethyl | ||
| 中文别名 | |||
| 英文别名 | LX-1606;LX 1606;LX1606; | ||
| SMILES | CCOC(=O)C(CC1=CC=C(C=C1)C2=CC(=NC(=N2)N)OC(C3=C(C=C(C=C3)Cl)N4C=CC(=N4)C)C(F)(F)F)N | ||
| 化学名称 | |||
| 分子式 | C27H26ClF3N6O3 | 分子量 | 574.98 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Telotristat Ethyl is the ethyl ester form of telotristat, a tryptophan hydroxylase (TPH) inhibitor, with potential anti-serotonergic activity. Upon administration, telotristat binds to and inhibits the activity of TPH. This may result in a reduction in peripheral serotonin (5-HT) production and improvement of serotonin-mediated gastrointestinal effects such as severe diarrhea. TPH, the rate-limiting enzyme in serotonin biosynthesis, is overexpressed in carcinoid tumor cells. | ||
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