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MI 2 MALT1 inhibitor 结构式

MI 2 MALT1 inhibitor

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP11666CAS号 :1047953-91-2纯度:98%
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  • 基本信息与产品描述
CAS号 1047953-91-2 货号 BCP11666
中文名 MI 2 MALT1 inhibitor
英文名 MI 2 MALT1 inhibitor
中文别名
英文别名 MI-2;MI2;
SMILES
化学名称
分子式 C19H17Cl3N4O3 分子量 455.72
纯度 98% 配送 惯例下常温包邮
产品描述 MI-2 selectively killed ABC-DLBCL cell lines with CD79A/B, CARMA1, and/or MYD88 mutations but not those occurring in proteins downstream of MALT1, including those with A20 homozygous deletion or TAK1 mutation. Both MI-2 and Z-VRPR-FMK reduced nuclear c-REL to a similar extent, without affecting whole-cell levels of this protein. In both cell lines, exposure to MI-2 caused a clear reduction of nuclear c-REL whereas it did not affect p65 levels.
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