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| CAS号 | 1082949-67-4 | 货号 | BCP14038 |
| 中文名 | LY2584702 | ||
| 英文名 | LY2584702 | ||
| 中文别名 | |||
| 英文别名 | LY 2584702;LY-2584702; LYS6K2; LYS-6K2; LYS 6K2; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C21H19F4N7 | 分子量 | 445.42 |
| 纯度 | 98 | 配送 | 惯例下常温包邮 |
| 产品描述 | LY-2584702 is an orally available inhibitor of p70S6K signaling, with potential antineoplastic activity. LY2584702 inhibits ribosomal protein S6 Kinase (p70S6K), and prevents phosphorylation of the S6 subunit of ribosomes, thereby inhibiting normal ribosomal function within tumor cells leading to a decrease in protein synthesis and in cellular proliferation. P70S6K, a serine/threonine kinase, acts downstream of PIP3 and phosphoinositide-dependent kinase-1 in the PI3 kinase pathway, is often upregulated in a variety of cancer cells, and is involved in the regulation of cell growth, proliferation, motility, and survival. | ||
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