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| CAS号 | 1202055-32-0 | 货号 | BCP28244 |
| 中文名 | NMS-P715 | ||
| 英文名 | NMS-P715 | ||
| 中文别名 | |||
| 英文别名 | NMSP715; NMSP 715; | ||
| SMILES | O=C(C1=NN(C)C2=C1CCC3=CN=C(NC4=CC=C(C(NC5CCN(C)CC5)=O)C=C4OC(F)(F)F)N=C23)NC6=C(CC)C=CC=C6CC | ||
| 化学名称 | |||
| 分子式 | C35H39F3N8O3 | 分子量 | 676.73 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | NMS-P715 is a selective and orally bioavailable MPS1 inhibitor, which selectively reduces cancer cell proliferation, leaving normal cells almost unaffected. NMS-P715 accelerates mitosis and affects kinetochore components localization causing massive aneuploidy and cell death in a variety of tumoral cell lines and inhibits tumor growth in preclinical cancer models. Inhibiting the SAC could represent a promising new approach to selectively target cancer cells. | ||
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