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| CAS号 | 1223498-69-8 | 货号 | BCP28164 |
| 中文名 | Roniciclib | ||
| 英文名 | Roniciclib | ||
| 中文别名 | |||
| 英文别名 | BAY1000394; BAY1000394; BAY 1000394; | ||
| SMILES | C[C@@H](O)[C@](OC1=NC(NC2=CC=C([C@@](=N)(C3CC3)=O)C=C2)=NC=C1C(F)(F)F)C | ||
| 化学名称 | |||
| 分子式 | C18H21F3N4O3S | 分子量 | 430.44 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Roniciclib, also known as BAY 1000394, is an orally bioavailable cyclin dependent kinase (CDK) inhibitor with potential antineoplastic activity. pan-CDK inhibitor BAY1000394 selectively binds to and inhibits the activity of CDK1/Cyclin B, CDK2/Cyclin E, CDK4/Cyclin D1, and CDK9/Cyclin T1, serine/threonine kinases that play key roles in the regulation of the cell cycle progression and cellular proliferation. Inhibition of these kinases leads to cell cycle arrest during the G1/S transition, thereby leading to an induction of apoptosis, and inhibition of tumor cell proliferation. | ||
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