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Quiflapon 结构式

喹夫拉朋

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货号 :BCP06574CAS号 :136668-42-3纯度:98%
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  • 基本信息与产品描述
CAS号 136668-42-3 货号 BCP06574
中文名 喹夫拉朋
英文名 Quiflapon
中文别名
英文别名 MK0591;MK 0591;MK-0591;
SMILES
化学名称
分子式 C34H35ClN2O3S 分子量 587.18
纯度 98% 配送 惯例下常温包邮
产品描述 MK-0591 is a synthetic compound which specifically inhibits the activity of 5-Lox and is currently under development for the treatment of asthma. Research of involvement of 5-lipoxygenase activating protein in the amyloidotic phenotype of an Alzheimer's disease mouse model showed that a novel functional role for 5-lipoxygenase activating protein in the pathogenesis of Alzheimer's disease-like amyloidosis, and suggest that its pharmacological inhibition could provide a novel therapeutic opportunity for Alzheimer's disease. Another research showed 5-Lipoxygenase-activating protein (FLAP) inhibitor MK-0591 prevents aberrant alveolarization in newborn mice exposed to 85% oxygen in a dose- and time-dependent manner.
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