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CAS号 | 936350-00-4 | 货号 | BCP30434 |
中文名 | Fiboflapon | ||
英文名 | Fiboflapon | ||
中文别名 | |||
英文别名 | AM-803; AM 803; AM803; GSK2190915;GSK-2190915; GSK 2190915; | ||
SMILES | CCOC1=NC=C(C=C1)C2=CC=C(C=C2)CN3C4=C(C=C(C=C4)OCC5=NC=C(C=C5)C)C(=C3CC(C)(C)C(=O)O)SC(C)(C)C | ||
化学名称 | |||
分子式 | C38H43N3O4S | 分子量 | 637.84 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Fiboflapon, also known as AM-803 and GSK2190915, is a potent, oral, once daily FLAP inhibitor (5-lipoxygenase-activating protein inhibitor). GSK2190915 attenuated the early (0-2 h) and late (4-10 h) asthmatic responses to inhaled allergen compared with placebo. GSK2190915 shows potential as a treatment for patients with asthma. Efficacy was demonstrated for GSK2190915 30 mg compared with placebo in day-time symptom scores and day-time SABA use. |
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