
氘可来昔替尼 新

规格 | 价格(CNY) | 是否现货 | 购买咨询 |
---|---|---|---|
5.00 mg | ¥1250.00 | In-stock | 购买咨询 |
10.00 mg | ¥2000.00 | In-stock | 购买咨询 |
25.00 mg | ¥3700.00 | In-stock | 购买咨询 |
50.00 mg | ¥5800.00 | In-stock | 购买咨询 |
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CAS号 | 1609392-27-9 | 货号 | BCP30443 |
中文名 | 氘可来昔替尼 | ||
英文名 | Deucravacitinib | ||
中文别名 | 氘可来替尼; | ||
英文别名 | BMS 986165; BMS986165;BMS-986165;Tyk2-IN-4; | ||
SMILES | CNC(=O)C1=NN=C(C=C1NC2=CC=CC(=C2OC)C3=NN(C=N3)C)NC(=O)C4CC4 | ||
化学名称 | |||
分子式 | C20H19D3N8O3 | 分子量 | 425.47 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | BMS-986165 is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease. MS-986165 potently binds to the Tyk2 pseudokinase domain (Ki = 0.02 nM), and is highly selective against a panel of 265 kinases and pseudokinases. The compound potently inhibited IL-23-, IL-12-, and Type I interferon-driven cellular signaling and transcriptional responses (IC50 range 2-14 nM). |
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