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| CAS号 | 202189-78-4 | 货号 | BCP02576 |
| 中文名 | 比拉斯汀 | ||
| 英文名 | Bilastine | ||
| 中文别名 | |||
| 英文别名 | Bilastinum;Ilaxten; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C28H37N3O3 | 分子量 | 463.61 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Bilastine binds to histamine H1-receptors as indicated by its displacement of [3H]-pyrilamine from H1-receptors expressed in guinea-pig cerebellum and human embryonic kidney (HEK) cell lines. The studies conducted on guinea-pig smooth muscle demonstrated the capability of bilastine to antagonise H1-receptors. Bilastine is selective for histamine H1-receptors as shown in receptor-binding screening conducted to determine the binding capacity of bilastine to 30 different receptors . Bilastine distribution has an apparent volume of distribution of 1.29 L/kg, and has an elimination half-life of 14.5 h and plasma protein binding of 84-90% . | ||
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