BIBN 4096BS

参考资料仅供科学研究，不可用于个人用途。

货号：BCP29403CAS号：204697-65-4纯度：98%

在线咨询

购买咨询

全国免运费！免费咨询：400-099-8200 或手机联系：13472751340

* 必填项

请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。

* Required Fields.

Please complete the form below and we will contact you shortly.

* Required Fields.

Please complete the form below and we will contact you shortly.

CAS号	204697-65-4	货号	BCP29403
中文名	BIBN 4096BS
英文名	BIBN 4096BS
中文别名
英文别名	BIBN-4096; BIBN4096; BIBN 4096; BIBN-4096BS; BIBN4096BS; Olcegepant;
SMILES	O=C1N(CC2=C(N1)C=CC=C2)C3CCN(C(N[C@@H](C(N[C@H](C(N4CCN(C5=CC=NC=C5)CC4)=O)CCCCN)=O)CC6=CC(Br)=C(C(Br)=C6)O)=O)CC3
化学名称
分子式	C38H47Br2N9O5	分子量	869.65
纯度	98%	配送	惯例下常温包邮
产品描述	BIBN 4096BS, also known as BIBN-4096 or Olcegepant is is the first potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor, a key modulator in neurogenic inflammatory pain. In preclinical studies, olcegepant attenuated arterial dilation induced by CGRP or electrical stimulation. In a phase II clinical trial, olcegepant reduced the severity of headache in 60% of migraine sufferers and met secondary endpoints including headache-free rate and rate of sustained response. The compound appears to be an effective anti-migraine medication that is well tolerated and does not display the vasoconstrictive effect that precludes the use of triptans and dihydroergotamine in certain patients.