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| CAS号 | 217094-32-1 | 货号 | BCP36167 |
| 中文名 | K-604 Dihydrochloride | ||
| 英文名 | K-604 Dihydrochloride | ||
| 中文别名 | |||
| 英文别名 | K-604 2HCl;K 604 Dihydrochloride;K604 Dihydrochloride; | ||
| SMILES | CC1=CC(=C(C(=N1)SC)NC(=O)CN2CCN(CC2)CCSC3=NC4=CC=CC=C4N3)SC.Cl.Cl | ||
| 化学名称 | |||
| 分子式 | C23H32Cl2N6OS3 | 分子量 | 575.63 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | K-604 dihydrochloride is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor with an IC50 of 0.45±0.06 μMK-604 is a potent and selective acyl-CoA:cholesterol acyltransferase 1 (ACAT-1) inhibitor. K-604 inhibits against acyl-coenzyme A (acyl-CoA):cholesterol O-acyltransferase-1 (ACAT1, SOAT1) activitiy in a selective (IC50 = 450 nM vs. 102.85 μ M against human.ACAT1 and ACAT2, respectively) and acyl-CoA-competitive (Ki = 378 nM against oleoyl-coA) manner. | ||
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