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Saxagliptin hydrochloride 结构式

沙格列汀盐酸盐

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货号 :BCP21271CAS号 :709031-78-7纯度:98%
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  • 基本信息与产品描述
CAS号 709031-78-7 货号 BCP21271
中文名 沙格列汀盐酸盐
英文名 Saxagliptin hydrochloride
中文别名 盐酸沙格列汀;
英文别名 Saxagliptin HCl;BMS477118; BMS 477118; BMS-477118;
SMILES C1C2CC2N(C1C#N)C(=O)C(C34CC5CC(C3)CC(C5)(C4)O)N.Cl
化学名称
分子式 C18H26ClN3O2 分子量 351.87
纯度 98% 配送 惯例下常温包邮
产品描述 Saxagliptin Hydrochloride is the hydrochloride salt form of saxagliptin, an orally bioavailable, potent, selective and competitive, cyanopyrrolidine-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Saxagliptin is metabolized into an, although less potent, active mono-hydroxy metabolite.Saxagliptin is a new oral hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin was approved in 2008 for the treatment of type 2 diabetes. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones, thereby increasing their bloodstream concentrations and reducing fasting and postprandial glucose concentrations in a glucose-dependent manner in patients with type 2 diabetes mellitus. .
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