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Tetrabenazine 结构式

Tetrabenazine

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP24156CAS号 :718635-93-9纯度:98%
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  • 基本信息与产品描述
CAS号 718635-93-9 货号 BCP24156
中文名 Tetrabenazine
英文名 Tetrabenazine
中文别名
英文别名 Ro 1-9569;
SMILES
化学名称
分子式 C19H27NO3 分子量 317.42
纯度 98% 配送 惯例下常温包邮
产品描述 The vesicular monoamine transporter type 2 (VMAT2) inhibitors are agents that cause a depletion of neuroactive peptides such as dopamine in nerve terminals and are used to treat chorea due to neurodegenerative diseases (such as Huntington chorea) or dyskinesias due to neuroleptic medications (tardive dyskinesia). As of 2019, three VMAT2 inhibitors have become available in the United States for management of dyskinesia syndromes, each with a somewhat different spectrum of approved indications: tetrabenazine (Xenazine and generics: 2008), deutetrabenazine (Austedo: 2017) and valbenazine (Ingressa: 2017). The VMAT2 inihibitors have not been associated with serum enzyme elevations during therapy or linked to instances of clinically apparent liver injury, but they have had limited general clinical use.
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