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AT7519 HCl 结构式

AT7519 HCl

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货号 ：BCP01950CAS号 ：902135-91-5纯度：98%
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  • 基本信息与产品描述
CAS号 902135-91-5 货号 BCP01950
中文名 AT7519 HCl
英文名 AT7519 HCl
中文别名
英文别名 AT 7519 HCl;AT-7519 HCl;AT7519 Hydrochloride ;AT-7519 Hydrochloride;AT 7519 Hydrochloride;
SMILES
化学名称
分子式 C16H17Cl2N5O2.HCl 分子量 418.71
纯度 98% 配送 惯例下常温包邮
产品描述 AT7519 HCl is a potent inhibitor of CDKs, with IC50s of 210, 47, 100, 13, 170, and <10 nM for CDK1, CDK2, CDK4 to CDK6, and CDK9, respectively.AT-7519 is an orally bioavailable small molecule CDK inhibitor with potential antineoplastic activity. AT7519M selectively binds to and inhibits cyclin dependent kinases (CDKs), which may result in cell cycle arrest, induction of apoptosis, and inhibition of tumor cell proliferation. CDKs are serine/theronine kinases involved in regulation of the cell cycle and may be overexpressed in some types of cancer cells.
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