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CAS号 | 1227633-49-9 | 货号 | BCP07738 |
中文名 | StemRegenin 1 | ||
英文名 | StemRegenin 1 | ||
中文别名 | |||
英文别名 | StemRegenin1;SR-1;SR1;SR 1; | ||
SMILES | |||
化学名称 | |||
分子式 | C24H23N5OS | 分子量 | 429.54 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | The compound StemRegenin 1 (SR1) is a selective, cell permeable, small molecule that promotes the self-renewal of human hematopoietic stem cells in culture. SR1 is an antagonist of the aryl hydrocarbon receptor.SR1 is the first small molecule that promotes robust expansion/self-renewal of human CD34+ peripheral blood and cord blood hematopoietic stem cells (HSCs). Culture of HSCs with SR1 led to a 50-fold increase in cells expressing CD34 and a 17-fold increase in cells that retain the ability to engraft immunodeficient mice. SR1 can be potentially used for ex vivo expansion of normal HSCs or leukemic stem/progenitor cells. |
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