维考西肽新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP25088CAS号：1262780-97-1纯度：98%

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CAS号	1262780-97-1	货号	BCP25088
中文名	维考西肽
英文名	Etelcalcetide
中文别名	维拉卡肽;
英文别名	AMG 416; KAI-4169;AMG416; KAI 4169;AMG-416; KAI4169;
SMILES	CC(C(=O)NC(CCCN=C(N)N)C(=O)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCCN=C(N)N)NC(=O)C(C)NC(=O)C(CSSCC(C(=O)O)N)NC(=O)C
化学名称
分子式	C38H73N21O10S2	分子量	1048.25
纯度	98%	配送	惯例下常温包邮
产品描述	Etelcalcetide is a calcimimetic and calcium-sensing receptor (CaSR) agonist composed of a synthetic peptide comprised of seven D-amino acids that can be used to treat secondary hyperparathyroidism (sHPT) in hemodialysis patients with chronic kidney disease (CKD). Upon intravenous administration, etelcalcetide mimics calcium and allosterically binds to and activates the CaSR expressed by the parathyroid gland. This suppresses the synthesis and secretion of parathyroid hormone (PTH), thereby reducing PTH levels and lowering serum calcium and phosphorus levels. Elevated PTH is often observed in patients with CKD and is associated with dysregulated calcium-phosphate homeostasis.

维考西肽 新