BAY57-1293 甲磺酸盐

参考资料仅供科学研究，不可用于个人用途。

货号：BCP20638CAS号：1428333-96-3纯度：98%

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CAS号	1428333-96-3	货号	BCP20638
中文名	BAY57-1293 甲磺酸盐
英文名	BAY57-1293 mesylate
中文别名
英文别名	Pritelivir mesylate;BAY57-1293; BAY 57-1293; BAY-57-1293; BAY571293; BAY 571293; BAY-571293; AIC-316; AIC 316; AIC316;
SMILES
化学名称
分子式	C18H18N4O3S2.CH4O3S	分子量	498.59
纯度	98%	配送	惯例下常温包邮
产品描述	Pritelivir, also known as AIC-316 and BAY 57-1293, is a potent helicase primase inhibitor. BAY 57-1293 inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the viral primase-helicase complex. In various rodent models of HSV infection the antiviral activity of BAY 57-1293 in vivo was found to be superior compared to all compounds currently used to treat HSV infections. The compound shows profound antiviral activity in murine and rat lethal challenge models of disseminated herpes, in a murine zosteriform spread model of cutaneous disease, and in a murine ocular herpes model. It is active in parenteral, oral, and topical formulations.