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Pritelivir 结构式

普瑞利韦

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货号 :BCP08742CAS号 :348086-71-5纯度:98%
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  • 基本信息与产品描述
CAS号 348086-71-5 货号 BCP08742
中文名 普瑞利韦
英文名 Pritelivir
中文别名
英文别名 BAY57-1293; BAY 57-1293; BAY-57-1293; BAY571293; BAY 571293; BAY-571293; AIC-316; AIC 316; AIC316;
SMILES
化学名称
分子式 C18H18N4O3S2 分子量 402.49
纯度 98% 配送 惯例下常温包邮
产品描述 Pritelivir is a potent helicase primase inhibitor. BAY 57-1293 inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the viral primase-helicase complex. In various rodent models of HSV infection the antiviral activity of BAY 57-1293 in vivo was found to be superior compared to all compounds currently used to treat HSV infections. The compound shows profound antiviral activity in murine and rat lethal challenge models of disseminated herpes, in a murine zosteriform spread model of cutaneous disease, and in a murine ocular herpes model. It is active in parenteral, oral, and topical formulations.
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