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| CAS号 | 518-82-1 | 货号 | BCP18372 |
| 中文名 | 大黄素 | ||
| 英文名 | Emodin | ||
| 中文别名 | |||
| 英文别名 | Emodol;Frangula emodin; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C15H10O5 | 分子量 | 270.24 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Emodin is a naturally-occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directly and selectively inhibits casein kinase II (IC50 = 0.89 μM). Through this action, it inhibits the COP9 signalosome, causing the stabilization of the tumor suppressor p53. Moreover, emodin acts as a phytoestrogen, binding human estrogen receptors and blocking 17β-estradiol binding with Ki values of 0.77 and 1.5 μM for ERα and ERβ, respectively. | ||
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