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| CAS号 | 75330-75-5 | 货号 | BCP20921 |
| 中文名 | 洛伐他汀 | ||
| 英文名 | Lovastatin | ||
| 中文别名 | |||
| 英文别名 | Mevinolin; Mevacor; Monacolin K; Altoprev; MK 803; MK-803; MK803; Monacolin K; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C24H36O5 | 分子量 | 404.54 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Lovastatin inhibits HMGCR, blocking the enzyme-catalyzed transformation of 3-hydroxy-3-methylglutaryl CoA into mevalonate. Lovastatin is a statin natural product isolated from numerous sources including the Pleurotus ostreatus oyster mushroom, demonstrating hypocholesterolemic and antiproliferative properties. The biosynthesis of cholesterol requires mevalonate as a building block and elimination of mevalonate generation subsequently interrupts cholesterol synthesis, leading to a reduction of circulating low-density lipoproteins. Lovastatin demonstrates arrest of the cell cycle at the G1 phase in bladder carcinoma T24 cells. | ||
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