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Alfuzosin hydrochloride 结构式

盐酸阿夫唑嗪

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货号 :BCP02086CAS号 :81403-68-1纯度:98%
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  • 基本信息与产品描述
CAS号 81403-68-1 货号 BCP02086
中文名 盐酸阿夫唑嗪
英文名 Alfuzosin hydrochloride
中文别名
英文别名 Uroxatral;
SMILES
化学名称
分子式 C19H27N5O4.HCl 分子量 425.91
纯度 98% 配送 惯例下常温包邮
产品描述 Alfuzosin, a new quinazoline derivative, acts as a selective and competitive antagonist of alpha 1-adrenoceptor-mediated contraction of prostatic, prostatic capsule, bladder base and proximal urethral smooth muscle, thereby reducing the tone of these structures. Consequently, urethral pressure and resistance, bladder outlet resistance, bladder instability and symptoms associated with benign prostatic hyperplasia are reduced. A limited range of clinical studies have shown oral alfuzosin to be more effective than placebo (in studies of < or = 6 months duration), to have sustained effects on long term administration (< or = 30 months), and to be comparable with the alpha 1-adrenoceptor antagonist prazosin, in the symptomatic treatment of benign prostatic hyperplasia. Oral alfuzosin 7.5 to 10 mg/day in divided doses appears to be a promising first-line agent for symptomatic treatment of noncomplicated mild to moderate benign prostatic hyperplasia in patients with a high dynamic component t
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