首页   >  
Angiogenesis/Protein Tyrosine Kinase
  >  
RET

所有产品分类

所有产品

信号通路

研究领域

天然产物

抗体

多肽

催化剂

杂质对照品

医药中间体

基础原料

RET

结构式 货号 产品名称 CAS号
APS-03118 结构式
BCP49314 APS-03118 APS-03118
APS03118 is a novel next-generation RET inhibitor which is potent against a range of RET fusions and mutations including both SFMs and gatekeeper mutations.
BT44 结构式
BCP48539 BT44 924759-42-2
BT44 is a novel RET agonist for the treatment of experimental neuropathies.
SPP-86 结构式
BCP46432 SPP-86 1357349-91-7
SPP-86 is a potent RET inhibitor.
TPX-0046 结构式
BCP43814 TPX-0046 TPX0046
TPX-0046 is a novel RET/SRC inhibitor with a mean IC50 of 17 nM for RETG810R in Ba/F3 cell proliferation assay.
Ret V804M-IN-1 结构式
BCP37566 Ret V804M-IN-1 2414909-94-5
Ret V804M-IN-1 is a wt-RET -selective inhibitors of RETV804M kinase, with an IC50 of 20 nM.
cis-Pralsetinib 结构式
BCP31224 cis-Pralsetinib 2097132-93-7
cis-Pralsetinib is a highly potent and selective inhibitor of rearranged during transfection (RET), with IC50 values ranging from 0.3 to 0.4 nM for WT RET and four enzyme variants (V804L, V804M, M918T, CCDC6-RET), and with broad, robust and anti-tumor activity against multiple RET-driven solid tumor types.
 结构式
BCP30970 GUN55146 2222755-14-6
LOXO-292 is a RET kinase inhibitor extracted from patent WO2018071447A1, Compound Example 552, has IC50s of 1 nM, 7 nM, and 101 nM for RET (WT), RET (V804M) , and RET (G810R), respectively .
Pralsetinib 结构式
BCP29411 拉西替尼 2097132-94-8
Pralsetinib (BLU-667) is a highly potent and selective RET inhibitor with an IC50 of 0.4 nM for wild type RET kinase.
RET Kinase inhibitor 1  结构式
BCP23560 RET Kinase inhibitor 1 1627856-64-7
GSK3179106 is a potent, selective, first-in-class and gut-restricted RET kinase inhibitor with IC50 of 0.4 and 11 nM in the biochemical assay and cellular assay respectively, 273-fold selectivity over KDR.
AD80 结构式
BCP25106 AD80 1384071-99-1
AD80, a multikinase inhibitor, inhibits RET, RAF,SRCand S6K, with greatly reduced mTOR activity.
12下一页共 19 条记录 1 / 2 页 
2853530910