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AZD-6126 结构式

AZD-6126

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货号 ：BCP04084CAS号 ：219923-05-4纯度：98%
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  • 基本信息与产品描述
CAS号 219923-05-4 货号 BCP04084
中文名 AZD-6126
英文名 AZD-6126
中文别名
英文别名 ANG453;AZD 6126;AZD6126;ANG 453;ANG-453;
SMILES
化学名称
分子式 C20H24NO8P 分子量 437.38
纯度 98% 配送 惯例下常温包邮
产品描述 AZD6126, also known as ANG-453, a water-soluble phosphate prodrug of N-acetylcolchinol with potential antiangiogenesis and antineoplastic activities. AZD-6126 is an angiogenesis inhibitor and tubulin inhibitor potentially for the treatment of solid tumours. AZD6126 is converted in vivo into N-acetylcolchinol. N-acetylcolchinol binds to and destabilizes the tubulin cytoskeleton of endothelial cells in tumor blood vessels, which may result in tumor endothelial cel apoptosis, the selective occlusion of tumor blood vessels, cessation of tumor blood flow, and tumor necrosis.
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